{"created":"2023-06-19T09:37:21.275506+00:00","id":935,"links":{},"metadata":{"_buckets":{"deposit":"1025e7ae-ea0a-4b95-a2cc-f65b894bd2d0"},"_deposit":{"created_by":2,"id":"935","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"935"},"status":"published"},"_oai":{"id":"oai:ngu.repo.nii.ac.jp:00000935","sets":["1:24:212"]},"author_link":["29","2183"],"item_10002_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"キカイテキソンショウノテイドノチガイガカルボニルストレスハツゲンニオヨボスエイキョウ"}]},"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-03-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"19","bibliographicPageStart":"11","bibliographicVolumeNumber":"5","bibliographic_titles":[{"bibliographic_title":"名古屋学院大学論集　医学・健康科学・スポーツ科学篇"},{"bibliographic_title":"THE NAGOYA GAKUIN DAIGAKU RONSHU; Journal of Nagoya Gakuin University; MEDICAL, HEALTH, and SPORTS SCIENCES\\n","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"　 Low back pain is a significant public health problem worldwide.  Intervertebral disc degeneration is most significant known risk factor for low back pain.  Yet the mechanisms of degeneration remain relatively unknown.  Carbonyl stress and oxidation have been implicated in cartilage and fibrocartilage degeneration.  Here we investigate the role of oxidative stress and carbonyl production in the intervertebral disc after mechanical injury using an in vitro organ model of the mouse functional spine unit.  We use a single- stab insult to model mild injury, and the three- stab insult to model severe trauma.  Our results indicate that mild injury increases the carbonyl response that may be required for tissue repair, while severe trauma tempers this response and rapidly accelerates degeneration.","subitem_description_type":"Abstract"}]},"item_10002_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.15012/00000924","subitem_identifier_reg_type":"JaLC"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"名古屋学院大学総合研究所"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2187-5162","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"日比野, 至"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"サイモン, タング"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-04-18"}],"displaytype":"detail","filename":"igakukenkou_vol0502_02.pdf","filesize":[{"value":"704.8 kB"}],"format":"application/pdf","license_note":"Copyright (c) 2017 日比野至,サイモンタング","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"igakukenkou_vol0502_02.pdf","url":"https://ngu.repo.nii.ac.jp/record/935/files/igakukenkou_vol0502_02.pdf"},"version_id":"2d3fb1b2-f151-4472-8934-1440ea557067"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"腰痛","subitem_subject_scheme":"Other"},{"subitem_subject":"椎間板","subitem_subject_scheme":"Other"},{"subitem_subject":"機械的損傷","subitem_subject_scheme":"Other"},{"subitem_subject":"カルボニルストレス","subitem_subject_scheme":"Other"},{"subitem_subject":"Low back pain","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Intervertebral disc degeneration","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Mechanical injury","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Carbonyl stress","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"機械的損傷の程度の違いがカルボニルストレス発現に及ぼす影響","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"機械的損傷の程度の違いがカルボニルストレス発現に及ぼす影響"},{"subitem_title":"Differential Carbonyl Stress Expression in the Intervertebral Disc between Singular- and Persistent- Mechanical Injuries","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"2","path":["212"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-04-18"},"publish_date":"2017-04-18","publish_status":"0","recid":"935","relation_version_is_last":true,"title":["機械的損傷の程度の違いがカルボニルストレス発現に及ぼす影響"],"weko_creator_id":"2","weko_shared_id":2},"updated":"2023-06-19T10:02:57.915467+00:00"}