@article{oai:ngu.repo.nii.ac.jp:00000397,
 author = {藤森, 修 and 赤木, 充宏 and 平林, 義章},
 issue = {2},
 journal = {名古屋学院大学論集　人文・自然科学篇, THE NAGOYA GAKUIN DAIGAKU RONSHU; Journal of Nagoya Gakuin University; HUMANITIES and NATURAL SCIENCES},
 month = {Jan},
 note = {Brachymorphic mice are characterized by disproportionally short limb and trunk, and short and thick tail. This disorder is induced by the bm gene. The bm gene is recessive autosomal gene and induces the point mutation in the sulfate groups convert enzymes in the sulfation pass way. Therefore, bm gene induces the undersulfation in many tissues, resulting chondrodystrophia in cartilage tissues.
The mice in approximately 3-5% of this strain are with anterior transverse malocclusion. Consequentially, we examined the morphological differences between normal and brachymorphic mice with or without the anterior transverse malocclusion.
To demonstrate the deformation of craniofacial complex and mandible, dry skeletons were prepared and a series of the length and width were measured. All data were compiled and the statistically significant differences between the data were determined by t-test. And moreover, we plotted each biometric point on the graphs.
As a result, when comparing between normal and brachymorphic mice,
1) Total length of craniofacial complex in brachymorphic mice was shorter than that of normal mice (approximately 20%). Especially, the decrease in the length of nasal and occipital region of craniofacial complex in the brachymorphic mice was prominent in comparison with the normal mice.
2) The length of mandible in brachymorphic mice was decreased approximately 10-15% compared to that of normal mice. Especially, the difference in the length of LB-G was noted between normal and brachymorphic mice.
3) When comparing the dental arch of normal and brachymorphic mice, the differences in the length of UB-M3 in the maxilla were more conspicuous than the differences in the length of LB-M3 in the mandible.
4) No significant differences were observed in the width of mandible (CO-CO and G-G) and molars (M1-M1 and M3-M3 in maxilla and mandible) in normal and brachymorphic mice.
When comparing between normal occlusion and anterior transverse malocclusion in the brachymorphic mice,
1) No significant differences were observed in most of the length and width between normal occlusion and anterior transverse malocclusion in the brachymorphic mice.
2) In the brachymorphic mice with anterior transverse malocclusion, the deformation in the incisive (premaxillary) bone was observed.
3) In the brachymorphic mice with anterior transverse malocclusion, the deformation in the mandibular bone was hardly observed.
4) The shift to the left of lower incisor in mandible was caused by the shift to the right of the incisive (premaxillary) bone.},
 pages = {31--45},
 title = {切歯交差咬合を発症する短肢症マウス頭蓋骨の骨計測に関する研究},
 volume = {47},
 year = {2011}
}