{"created":"2023-06-19T09:37:33.981080+00:00","id":1332,"links":{},"metadata":{"_buckets":{"deposit":"5cad9c4f-1252-4591-bfbb-0269b784a351"},"_deposit":{"created_by":27,"id":"1332","owners":[27],"pid":{"revision_id":0,"type":"depid","value":"1332"},"status":"published"},"_oai":{"id":"oai:ngu.repo.nii.ac.jp:00001332","sets":["1:12:278"]},"author_link":["2114","2113","1729","2116","2117","33","32","2118","2115"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-01-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"27","bibliographicPageStart":"19","bibliographicVolumeNumber":"57","bibliographic_titles":[{"bibliographic_title":"名古屋学院大学論集　人文・自然科学篇"},{"bibliographic_title":"THE NAGOYA GAKUIN DAIGAKU RONSHU; Journal of Nagoya Gakuin University; HUMANITIES and NATURAL SCIENCES","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":" The medicinal plant Rabdosia excisa in the Lamiaceae family is found in Northeastern China and is used to treat a fever due to a cold, mastitis, arthralgia, and bruises[1]. A previous study reported that an aqueous extract from that plant yielded ent -kaurene diterpenes with antitumor action. In addition, diterpenes have been used to synthesize analogs in relatively large quantities, and their structureactivity relationship in terms of cytotoxic activity[2] and inhibition of the activation of the intracellular transcription factor NF-κB[3] has been examined. Various studies have also examined ent -kaurene diterpenes[4] ― [7]. Three diterpenes―kamebakaurin (1), kamebanin (2), and excisanin A (3)―can be obtained in relatively large quantities from R. excisa . The current study examined the effects of those diterpenes on cardiac function in guinea pigs. Some of those findings are reported here.","subitem_description_type":"Abstract"}]},"item_10002_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.15012/00001295","subitem_identifier_reg_type":"JaLC"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"名古屋学院大学総合研究所"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0385-0056","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Mitsui-Saitoh, Kumiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Aoyagi, Yutaka"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hitotsuyanagi, Yukio"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takeya, Koichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ming-Yu, Gui"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yong-Ri, Jin"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Xu-Wen, LI"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sakai, Junichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hotta, Yoshihiro"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-02-08"}],"displaytype":"detail","filename":"jinbun_vol5702_02.pdf","filesize":[{"value":"362.9 kB"}],"format":"application/pdf","license_note":"Copyright (c) 2020 Saitoh-Mitsui Kumiko,Aoyagi Yutaka,Hitotsuyanagi Yukio,Takeya Koichi,Ming-Yu Gui,Yong-Ri Jin,Xu-Wen LI,Sakai Junichi,Hotta ","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"jinbun_vol5702_02","url":"https://ngu.repo.nii.ac.jp/record/1332/files/jinbun_vol5702_02.pdf"},"version_id":"8c1a1b98-f1c8-402b-b759-37d4c2ff8929"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Rabdosia excisa (Labiatae)","subitem_subject_scheme":"Other"},{"subitem_subject":"ent -Kaurene diterpenoids","subitem_subject_scheme":"Other"},{"subitem_subject":"Positive inotropic effect (PIE)","subitem_subject_scheme":"Other"},{"subitem_subject":"Positive chronotropic effect (PCE)","subitem_subject_scheme":"Other"},{"subitem_subject":"Heart rate (HR)","subitem_subject_scheme":"Other"},{"subitem_subject":"Rabdosia excisa (Labiatae)","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ent -Kaurene diterpenoids","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Positive inotropic effect (PIE)","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Positive chronotropic effect (PCE)","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Heart rate (HR)","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effects of ent -Kaurene diterpenes from Rabdosia excisa on the cardiac function of guinea pigs","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effects of ent -Kaurene diterpenes from Rabdosia excisa on the cardiac function of guinea pigs"},{"subitem_title":"Effects of ent -Kaurene diterpenes from Rabdosia excisa on the cardiac function of guinea pigs","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"27","path":["278"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-02-10"},"publish_date":"2021-02-10","publish_status":"0","recid":"1332","relation_version_is_last":true,"title":["Effects of ent -Kaurene diterpenes from Rabdosia excisa on the cardiac function of guinea pigs"],"weko_creator_id":"27","weko_shared_id":-1},"updated":"2023-06-19T10:02:33.641007+00:00"}