@article{oai:ngu.repo.nii.ac.jp:00001332, author = {Mitsui-Saitoh, Kumiko and Aoyagi, Yutaka and Hitotsuyanagi, Yukio and Takeya, Koichi and Ming-Yu, Gui and Yong-Ri, Jin and Xu-Wen, LI and Sakai, Junichi and Hotta, Yoshihiro}, issue = {2}, journal = {名古屋学院大学論集 人文・自然科学篇, THE NAGOYA GAKUIN DAIGAKU RONSHU; Journal of Nagoya Gakuin University; HUMANITIES and NATURAL SCIENCES}, month = {Jan}, note = {The medicinal plant Rabdosia excisa in the Lamiaceae family is found in Northeastern China and is used to treat a fever due to a cold, mastitis, arthralgia, and bruises[1]. A previous study reported that an aqueous extract from that plant yielded ent -kaurene diterpenes with antitumor action. In addition, diterpenes have been used to synthesize analogs in relatively large quantities, and their structureactivity relationship in terms of cytotoxic activity[2] and inhibition of the activation of the intracellular transcription factor NF-κB[3] has been examined. Various studies have also examined ent -kaurene diterpenes[4] ― [7]. Three diterpenes―kamebakaurin (1), kamebanin (2), and excisanin A (3)―can be obtained in relatively large quantities from R. excisa . The current study examined the effects of those diterpenes on cardiac function in guinea pigs. Some of those findings are reported here.}, pages = {19--27}, title = {Effects of ent -Kaurene diterpenes from Rabdosia excisa on the cardiac function of guinea pigs}, volume = {57}, year = {2021} }